Welcome to Zhenghua Nie's homepage!

Zhenghua Nie, PhD

Email: niez at mcmaster dot ca

Papers, Posters, Software and Talks

Zhenghua Nie, Simulation and Optimal Design of Nuclear Magnetic Resonance Experiments, Open Access Dissertations and Theses, Paper 5543. July 2011. (abstract, pdf)

John Fox, Jarrett Byrnes, Zhenghua Nie, sem: Structural Equation Models, R package version 3.0. (sem 3.0)

Jeffrey S. Racine, Zhenghua Nie, crs: Categorical Regression Splines. R package, 2011. (R Package, faq) (including a simple R interface to NOMAD)

Christopher Kumar Anand, Alex D. Bain, Andrew Thomas Curtis, Zhenghua Nie, Designing Optimal Universal Pulses Using Second-Order, Large-Scale, Nonlinear Optimization, Journal of Magnetic Resonance (submitted) (Optimal Broadband Universal Rotation pulse: OBUR-180-9)

Alex D. Bain, Christopher Kumar Anand, Zhenghua Nie, Optimizing Phases of CPMG Pulse Sequence and Applying Exact Solution to Measure Relaxation Time, Canadian Operational Research Society (CORS) Annual Conference 2011, St. John's, Canada. (slides)

Christopher Kumar Anand, Alex D. Bain, Zhenghua Nie, Numeric-Symbolic Solutions of the Liouville-von Neumann Equation, Constrained Optimization, and NMR, Southern Ontario Numerical Analysis Day (SONAD 2011), May 13, 2011, McMaster University. (slides)

Alex D. Bain, Christopher Kumar Anand, Zhenghua Nie, Exact Solution of the CPMG Pulse Sequence with Phase Variation Down the Echo Train: Application to R₂ Measurements, Journal of Magnetic Resonance, 209 (2011) 183-194. (doi:10.1016/j.jmr.2011.01.009) (highlights)

Alex D. Bain, Christopher Kumar Anand, Zhenghua Nie, Solving the Bloch Equations: Application to the Hahn Echo , Small Molecule NMR Conference (SMASH 2010), Sep. 2010, Portland, Oregon, USA (abstract, poster)

Alex D. Bain, Christopher Kumar Anand, Zhenghua Nie, Measuring NMR Relaxation Time Using an Exact Solution of the Bloch Equations, Modeling and Optimization: Theory and Applications (MOPTA 2010), Aug. 2010, Lehigh University, USA (abstract, slides)

Alex D. Bain, Christopher Kumar Anand, Zhenghua Nie, Exact Solution to the Bloch Equations and Application to the Hahn Echo, Journal of Magnetic Resonance, 206 (2010) 227-240. (doi:10.1016/j.jmr.2010.07.012) (C Code of the Exact Solution of Bloch Equations and its Derivatives)

Alex D. Bain, Donald W. Hughes, Christopher K. Anand, Zhenghua Nie and Valerie J. Robertson, Problems, Artifacts and Solutions in the INADEQUATE NMR Experiment, Magnetic Resonance in Chemistry, 48 (2010) 630-641. (doi:10.1002/mrc.2639)

Christopher Kumar Anand, Alex D. Bain, Zhenghua Nie, Symbolic Construction of Spin Systems of the Liouville Space Method and its Applications,15th International Conference Applications of Computer Algebra (ACA 2009), École de technologie supérieure (ÉTS), June 25-28, 2009, Montréal, Québec, Canada (abstract)

Alex D Bain, Donald W. Hughes, Bob Berno, Zhenghua Nie, Valerie J. Robertson The Shortcomings of INADEQUATE, the 50th ENC, March 29 - April 3, 2009, California, USA (abstract)

Christopher Kumar Anand, Alex D. Bain, Andrew Curtis, Zhenghua Nie, Design of a Universal Refocusing Pulse by Large-scale Nonlinear Optimization, Small Molecule NMR Conference (SMASH), Sep. 2008, Santa Fe, New Mexico, USA (poster)

Christopher Kumar Anand, Alex D. Bain, Andrew Curtis, Zhenghua Nie, Optimal Pulse Design of Single Spin Systems, Modeling and Optimization: Theory and Applications (MOPTA), Aug. 2008, University of Guelph, Canada (abstract, slides)

Christopher Kumar Anand, Alex D. Bain, Zhenghua Nie, NMR Pulse Design Using Modern Optimization Methods, the 49th ENC, March 2008, California, USA (abstract, poster)

Christopher Kumar Anand, Alex D. Bain, Zhenghua Nie, Simulation of Steady-State NMR of Coupled Systems Using Liouville Space and Computer Algebra Methods, Journal of Magnetic Resonance, 189 (2007) 200-208. (doi:10.1016/j.jmr.2007.09.012)

Christopher Kumar Anand, Alex D. Bain, Zhenghua Nie, Optimal NMR Pulse Sequence for Detecting NAA using Liouvillian Space and Symbolic Computation, ICCOPT II & MOPTA-07, Aug. 2007, McMaster University, Canada (poster)

Christopher Kumar Anand, Alex D. Bain, Zhenghua Nie, Steady State Spectroscopy - CW NMR Lives! , 19th Annual MOOT Conference, Sep. 2006, University of Guelph, Canada (poster)

Christopher Kumar Anand, Alex D. Bain, Zhenghua Nie, The Simulation and Optimization of NMR Experiments using a Liouville Space Method, The Maple Conference, Waterloo, Canada, (2006): 203-216. (pdf, slides, Maple Worksheet)

NMR Animations

Tracing the mangetization (single spin-1/2) during a pulse. Relaxation is considered in the simulation.

All of the following animations are generated using the gif terminal of gnuplot.

Inversion Pulse (Soft Square π Pulse)

Inversion Pulse (Composite Pulse 90_x180_y90_x)

Inversion Pulse (OBUR-180-9)

Refocussing Pulse (Soft Square π Pulse)

Refocussing Pulse (OBUR-180-9)

Parameters and more animations are available here.